Current Issue : January - March Volume : 2021 Issue Number : 1 Articles : 5 Articles
Background: The phase correction on transcranial focused ultrasound is essential to regulate unwanted focal point\nshift caused by skull bone aberration. The aim of the current study was to design and investigate the feasibility of a\nray-based phase correction toolkit for transcranial focused ultrasound...........
Background: Robot assisted surgery has expanded considerably in the past years. Compared to conventional open\nor laparoscopic surgery, virtual reality (VR) training is an essential component in learning robot assisted surgery.\nHowever, for tasks to be implemented in a curriculum, the levels of validity should be studied for proficiency-based\ntraining. Therefore, this study was aimed to assess the validity evidence of advanced suturing tasks on a robot\nassisted VR simulator....
Background:The progressive evolution in hip replacement research is directed to\nfollow the principles of bone and soft tissue sparing surgery. Regarding hip implants,\na renewed interest has been raised towards short uncemented femoral implants. A\nheterogeneous group of short stems have been designed with the aim to approximate\ninitial, post-implantation bone strain to the preoperative levels in order to minimize the\neffects of stress shielding. This study aims to investigate the biomechanical properties\nof two distinctly designed femoral implants, the TRI-LOCK Bone Preservation Stem, a\nshortened conventional stem and the Minima S Femoral Stem, an even shorter and\nanatomically shaped stem, based on experiments and numerical simulations. Furthermore,\nfinite element models of implantâ??bone constructs should be evaluated for their\nvalidity against mechanical tests wherever it is possible. In this work, the validation was\nperformed via a direct comparison of the FE calculated strain fields with their experimental\nequivalents obtained using the digital image correlation technique....
Bone growth and metabolism are mainly regulated by a series of intracellular molecules and extracellular stimuli. Exosome, as a\nnanoscale substance secreted to the outside of the cells, plays an extensive role in intercellular communication. This review\nprovides theoretical references and evidences for further exploration of exosomes as noncoding RNA carriers to regulate bone\ntissue recovery through the following aspects: (1) basic characteristics of exosomes, (2) research progress of exosomal noncoding\nRNA in bone tissue engineering, (3) current status and advantages of engineering exosomes as nanocarriers for noncoding RNA\ndelivery, and (4) problems and application prospects of exosome therapy in the field of orthopedics....
Background: Alzheimerâ??s Disease (AD) is a degenerative brain disorder that often\noccurs in people over 65 years old. As advanced AD is difficult to manage, accurate\ndiagnosis of the disorder is critical. Previous studies have revealed effective deep learning\nmethods of classification. However, deep learning methods require a large number\nof image datasets. Moreover, medical images are affected by various environmental\nfactors. In the current study, we propose a deep learning-based method for diagnosis\nof Alzheimerâ??s disease (AD) that is less sensitive to different datasets for external validation,\nbased upon F-18 fluorodeoxyglucose positron emission tomography/computed\ntomography (FDG-PET/CT)....
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